tert-butyl 3-acetylpiperidine-1-carboxylate

tert-butyl 3-acetylpiperidine-1-carboxylate - Names and Identifiers

Name	1-Piperidinecarboxylic acid, 3-acetyl-, 1,1-dimethylethyl ester
Synonyms	1-Boc-3-acetylpiperidine tert-butyl 3-acetylpiperidine-1-carboxylate 1,1-Dimethylethyl 3-acetyl-1-piperidinecarboxylate 3-Acetyl-1-piperidinecarboxylic acid tert-butyl ester 3-Acetyl-piperidine-1-carboxylic acid tert-butyl ester 1-Piperidinecarboxylic acid, 3-acetyl-, 1,1-dimethylethyl es... 1-Piperidinecarboxylic acid, 3-acetyl-, 1,1-dimethylethyl ester 1-Piperidinecarboxylic acid, 3-acetyl-, 1,1-diMethylethyl ester 3-Acetyl-piperidine-1-carboxylic acid tert-butyl ester, Fandachem
CAS	858643-92-2
EINECS	200-589-5

tert-butyl 3-acetylpiperidine-1-carboxylate - Physico-chemical Properties

Molecular Formula	C12H21NO3
Molar Mass	227.3
Density	1.052
Boling Point	312.4±35.0 °C(Predicted)
pKa	-2.40±0.40(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

tert-butyl 3-acetylpiperidine-1-carboxylate - Introduction

1-Piperidinecarboxylic acid, 3-acetyl-, 1,1-dimethylethyl ester is an organic compound with the chemical formula C13H21NO3. The following is a detailed description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless liquid or solid
-Solubility: Soluble in organic solvents such as ethanol, chloroform and dimethylformamide
-Melting point: approx. 50-60°C
-Boiling point: about 340°C
-Density: approx. 1.02g/cm³

Use:
- 1-Piperidinecarboxylic acid, 3-acetyl-, 1,1-dimethylethyl ester can be used as an important intermediate and catalyst in organic synthesis, and is often used in the synthesis of drugs and pesticides.
-It can also be used as an additive for solvents, fragrances and cosmetic ingredients.
-Due to its special structure, it can generate other organic compounds through chemical reactions and has a wide range of applications.

Preparation Method:
-Synthesis by the reaction of acetic anhydride and tert-butyl piperidinecarboxylate, usually under an inert atmosphere.
-The synthesis reaction requires the use of solvents and catalysts, and the reaction conditions and specific methods can be adjusted as needed.

Safety Information:
- 1-Piperidinecarboxylic acid, 3-acetyl-, 1,1-dimethylethyl ester is a relatively safe compound according to the current research results.
-However, as a compound, it still has certain potential risks, and the following points need to be paid attention to during use:
-Keep away from fire and high temperature environment to avoid possible fire or explosion.
-Avoid contact with substances such as strong oxidants to prevent possible reactions and dangers.
-Avoid inhalation, ingestion or contact with skin and eyes to avoid poisoning or irritation.
-Use in a well-ventilated area and wear personal protective equipment, such as gloves, goggles and face shields.
-In case of accidental inhalation or contact, wash the affected area immediately and seek medical help.

Please note that the above is for informational purposes only. In practical application, the relevant safety operation procedures should be followed, and the evaluation and appropriate measures should be taken according to the specific situation.

Last Update：2024-04-09 21:04:16